In Hyde Park, social isolation was correlated with all of the social determinants of vulnerability as well as each other (r ≥ 0.74, P < 0.01). Hyde Park had the third largest percent of older adults as well as multiple areas with high concentrations of older adults. Additionally, over 70% of the population was people of color who are concentrated within multiple areas of the neighborhood. Like Fenway/Kenmore, there are populations with socially vulnerable characteristics that occur in small numbers in Hyde Park. Interestingly, Hyde Park had the smallest percentages of people who rent or have a medical illness and the second smallest percent of people who do not have a vehicle.